Therapeutic strategies for enhancing angiogenesis in wound healing

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Angiogenesis in Wound Healing

Angiogenesis, the formation of new blood vessels from pre-existing, vessels is a crucial process for tumor growth and metastasis (Folkman 1990; Kaafarani, Fernandez-Sauze et al. 2009). The new vessels supply the tumor cells with nutrients and oxygen and ensure efficient drainage of metabolites. Under normal conditions, a tissue or tumor cannot grow beyond 1 to 2 mm in diameter without neovascul...

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Fibromodulin Enhances Angiogenesis during Cutaneous Wound Healing

BACKGROUND Fibromodulin (FMOD) plays a critical role in the wound-healing process. Our previous studies revealed that FMOD deficiency led to marked alterations in adult wound healing characterized by delayed dermal cell migration, postponed wound closure, and increased scar formation, all accompanied by impeded angiogenesis. Therefore, the aim of this study was to reveal the effect of FMOD on a...

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Therapeutic Potential of Plants in Wound Healing

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ژورنال

عنوان ژورنال: Advanced Drug Delivery Reviews

سال: 2019

ISSN: 0169-409X

DOI: 10.1016/j.addr.2018.09.010